Silab develops anti-ageing active from peach tree leaves

Silab has launched Vitagenyl, an active ingredient rich in purified α-glucans (Prunus persica) derived from peach tree leaves with properties said to improve vitality and regeneration potential in ageing skin.

According to the manufacturer, the active is an adaptative ingredient for a new anti-ageing strategy as it contributes to the skin’s capacity to regenerate and accelerates its renewal.

It is now known that micro stress can be beneficial to skin as it stimulates skin cells to develop natural repair and defense mechanisms, thereby slowing down the ageing process, known as the hormesis principal,” says Silab.

Vitagenyl features this hormetic action, meaning that the cells are therefore better prepared and armed to fight subsequent stress. As a result of this, skin is regenerated and revitalised and the signs of ageing are less pronounced.

Trials

According to Silab, the effect of Vitagenyl on cell growth tested at 1 per cent significantly stimulated the viability of fibroblasts in a depleted medium by 22 per cent.

The active, again tested at 1 per cent “significantly increased Ki67 synthesis by 39 per cent. In a dose-dependent and hormetic manner, it also stimulated the capacity of human fibroblasts to flourish.”

Vitagenyl also significantly increases the expression of chaperone proteins and reduces the roughness parameters Sa in 61 per cent of volunteers and attenuates wrinkles by a significant reduction of volume in 56 per cent.

Overall, the anti-wrinkle regenerating effect “formulated at 3 per cent smoothed the skin surface on crow’s feet, as a result over 70 per cent of the volunteers noted a decrease in crow’s feet wrinkles”, Silab concluded.